Authors: Saeid Safiri; Seyed Ehsan Mousavi; Seyed Aria Nejadghaderi; Maryam Noori; Mark J. M. Sullman; Ali-Asghar Kolahi; Reza Shekarriz-Foumani · Research
What Is The Burden of Depression in the Middle East and North Africa?
An analysis of depression's impact across 21 countries reveals concerning trends and opportunities for intervention
Source: Safiri, S., Mousavi, S. E., Nejadghaderi, S. A., Noori, M., Sullman, M. J. M., Kolahi, A. A., & Shekarriz-Foumani, R. (2024). The burden of major depressive disorder in the Middle East and North Africa region, 1990-2019. Acta Neuropsychiatrica, 36, 139-152.
What you need to know
- Major depressive disorder affects over 20 million people in the Middle East and North Africa region
- The condition peaks in adults aged 35-39 and affects both men and women similarly
- Early detection and treatment are critical but cultural stigma often prevents people from seeking help
The Hidden Impact of Depression
Sarah had always been a high achiever, but lately, even getting out of bed felt impossible. Her family told her to “snap out of it” and pray more, but the darkness wouldn’t lift. Like millions across the Middle East and North Africa, Sarah was struggling with major depressive disorder (MDD), a serious condition that often goes unrecognized and untreated in the region.
Understanding the Scale of the Problem
Recent research reveals that over 20 million people in the Middle East and North Africa (MENA) region live with major depressive disorder. That’s roughly equivalent to the entire population of Sri Lanka. The condition affects about 3,322 people per 100,000 population, making it one of the leading causes of disability in the region.
Unlike what many believe, depression isn’t just feeling sad. It’s a complex medical condition that affects how people think, feel, and handle daily activities. The research shows that in the MENA region, depression typically starts affecting people in their early twenties, peaks between ages 35-39, and can continue throughout life if left untreated.
Cultural Context and Challenges
One of the most striking findings is how cultural factors influence depression in the MENA region. While the condition affects both men and women similarly, cultural stigma often prevents people from seeking help. In many MENA countries, mental health issues are still seen as a sign of weakness or lack of faith, rather than a medical condition requiring treatment.
The burden of depression varies significantly across countries in the region. Palestine, Morocco, and Tunisia show the highest rates, while the United Arab Emirates, Iraq, and Turkey have lower rates. These differences likely reflect various factors, including social stability, economic conditions, and access to mental health care.
The Economic and Social Impact
Depression isn’t just a personal struggle – it’s a significant public health challenge that affects entire communities. The condition leads to lost productivity, increased healthcare costs, and strain on families. In Iran alone, the economic burden of depression was estimated at USD 5.3 billion in 2020.
More concerning is that only one in 27 people with depression in low- and middle-income countries receives adequate treatment, compared to one in five in high-income countries. This treatment gap has serious consequences for individuals and societies.
What This Means for You
If you or someone you know is experiencing symptoms of depression, remember:
- Depression is a real medical condition, not a personal weakness
- Early treatment leads to better outcomes
- Help is available, even if cultural barriers make it seem difficult to access
- Primary care doctors can be a good first step for seeking help
- Supporting someone with depression involves understanding and patience
Conclusions
- Depression is a significant public health challenge in the MENA region that requires immediate attention
- Cultural stigma and limited access to care remain major barriers to treatment
- Investing in mental health services and education could significantly improve outcomes for millions of people